2d7u: Difference between revisions

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[[Image:2d7u.gif|left|200px]]<br /><applet load="2d7u" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2d7u, resolution 2.50&Aring;" />
'''Crystal structure of hypothetical adenylosuccinate synthetase, PH0438 from Pyrococcus horikoshii OT3'''<br />


==About this Structure==
==Crystal structure of hypothetical adenylosuccinate synthetase, PH0438 from Pyrococcus horikoshii OT3==
2D7U is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Active as [http://en.wikipedia.org/wiki/Adenylosuccinate_synthase Adenylosuccinate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.4.4 6.3.4.4] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D7U OCA].
<StructureSection load='2d7u' size='340' side='right'caption='[[2d7u]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
[[Category: Adenylosuccinate synthase]]
== Structural highlights ==
[[Category: Pyrococcus horikoshii]]
<table><tr><td colspan='2'>[[2d7u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii_OT3 Pyrococcus horikoshii OT3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D7U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D7U FirstGlance]. <br>
[[Category: Single protein]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
[[Category: Kishisita, S.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d7u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d7u OCA], [https://pdbe.org/2d7u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d7u RCSB], [https://www.ebi.ac.uk/pdbsum/2d7u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d7u ProSAT], [https://www.topsan.org/Proteins/RSGI/2d7u TOPSAN]</span></td></tr>
[[Category: Murayama, K.]]
</table>
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
== Function ==
[[Category: Shirouzu, M.]]
[https://www.uniprot.org/uniprot/PURA_PYRHO PURA_PYRHO] Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
[[Category: Xie, Y.]]
== Evolutionary Conservation ==
[[Category: Yokoyama, S.]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: conserved hypothetical protein]]
Check<jmol>
[[Category: national project on protein structural and functional analyses]]
  <jmolCheckbox>
[[Category: nppsfa]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d7/2d7u_consurf.spt"</scriptWhenChecked>
[[Category: riken structural genomics/proteomics initiative]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: rsgi]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: structural genomics]]
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2d7u ConSurf].
<div style="clear:both"></div>


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:56:00 2008''
==See Also==
*[[Adenylosuccinate synthetase 3D structures|Adenylosuccinate synthetase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Pyrococcus horikoshii OT3]]
[[Category: Kishisita S]]
[[Category: Murayama K]]
[[Category: Shirouzu M]]
[[Category: Xie Y]]
[[Category: Yokoyama S]]