2ddj: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
 
(14 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:2ddj.jpg|left|200px]]<br /><applet load="2ddj" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2ddj" />
'''NMR structure of the second Kunitz domain of human WFIKKN1'''<br />


==About this Structure==
==NMR structure of the second Kunitz domain of human WFIKKN1==
2DDJ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DDJ OCA].  
<StructureSection load='2ddj' size='340' side='right'caption='[[2ddj]]' scene=''>
 
== Structural highlights ==
==Reference==
<table><tr><td colspan='2'>[[2ddj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DDJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DDJ FirstGlance]. <br>
Second Kunitz-type protease inhibitor domain of the human WFIKKN1 protein., Liepinsh E, Nagy A, Trexler M, Patthy L, Otting G, J Biomol NMR. 2006 May;35(1):73-8. Epub 2006 Jun 1. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16791741 16791741]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ddj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ddj OCA], [https://pdbe.org/2ddj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ddj RCSB], [https://www.ebi.ac.uk/pdbsum/2ddj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ddj ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/WFKN1_HUMAN WFKN1_HUMAN] Protease-inhibitor that contains multiple distinct protease inhibitor domains. Probably has serine protease- and metalloprotease-inhibitor activity (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dd/2ddj_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ddj ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Liepinsh, E.]]
[[Category: Liepinsh E]]
[[Category: Otting, G.]]
[[Category: Otting G]]
[[Category: kunitz domain]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:57:45 2008''