4gmv: Difference between revisions

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{{STRUCTURE_4gmv|  PDB=4gmv  |  SCENE=  }}
===Crystal Structure of the coiled-coil, RA and PH domains of Lamellipodin===
{{ABSTRACT_PUBMED_23483482}}


==Function==
==Crystal Structure of the coiled-coil, RA and PH domains of Lamellipodin==
[[http://www.uniprot.org/uniprot/RAPH1_HUMAN RAPH1_HUMAN]] Mediator of localized membrane signals. Implicated in the regulation of lamellipodial dynamics. Negatively regulates cell adhesion.
<StructureSection load='4gmv' size='340' side='right'caption='[[4gmv]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[4gmv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GMV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GMV FirstGlance]. <br>
[[4gmv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GMV OCA].  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.403&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gmv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gmv OCA], [https://pdbe.org/4gmv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gmv RCSB], [https://www.ebi.ac.uk/pdbsum/4gmv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gmv ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RAPH1_HUMAN RAPH1_HUMAN] Mediator of localized membrane signals. Implicated in the regulation of lamellipodial dynamics. Negatively regulates cell adhesion.
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Chang, Y C.E.]]
[[Category: Large Structures]]
[[Category: Wu, J.]]
[[Category: Chang YCE]]
[[Category: Cell adhesion]]
[[Category: Wu J]]
[[Category: Cell migration]]
[[Category: Coiled-coil region]]
[[Category: Cytoskeletal protein]]
[[Category: Ena/vasp binding]]
[[Category: Pleckstrin homology domain]]
[[Category: Ra-ph]]
[[Category: Ras-association domain]]