4gzu: Difference between revisions

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{{STRUCTURE_4gzu|  PDB=4gzu  |  SCENE=  }}
===Crystal strucure of the DH-PH-PH domain of FARP2===
{{ABSTRACT_PUBMED_23375260}}


==Function==
==Crystal structure of the DH-PH-PH domain of FARP2==
[[http://www.uniprot.org/uniprot/FARP2_MOUSE FARP2_MOUSE]] Rho-guanine nucleotide exchange factor that activates RAC1. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton.<ref>PMID:12351724</ref><ref>PMID:16286926</ref>  
<StructureSection load='4gzu' size='340' side='right'caption='[[4gzu]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[4gzu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GZU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GZU FirstGlance]. <br>
[[4gzu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GZU OCA].  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gzu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gzu OCA], [https://pdbe.org/4gzu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gzu RCSB], [https://www.ebi.ac.uk/pdbsum/4gzu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gzu ProSAT]</span></td></tr>
==Reference==
</table>
<references group="xtra"/><references/>
== Function ==
[https://www.uniprot.org/uniprot/FARP2_MOUSE FARP2_MOUSE] Rho-guanine nucleotide exchange factor that activates RAC1. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton.<ref>PMID:12351724</ref> <ref>PMID:16286926</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: He, X.]]
[[Category: He X]]
[[Category: Zhang, X.]]
[[Category: Zhang X]]
[[Category: Dhph]]
[[Category: Farp2]]
[[Category: Gef]]
[[Category: Guanine nucleotide exchange factor]]
[[Category: Signaling protein]]
Retrieved from "https://proteopedia.org/4gzu"