4hj2: Difference between revisions

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{{STRUCTURE_4hj2|  PDB=4hj2  |  SCENE=  }}
===Crystal Structure Analysis of GSTA1-1 in complex with chlorambucil===
{{ABSTRACT_PUBMED_23460799}}


==Function==
==Crystal Structure Analysis of GSTA1-1 in complex with chlorambucil==
[[http://www.uniprot.org/uniprot/GSTA1_HUMAN GSTA1_HUMAN]] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.<ref>PMID:20606271</ref>  
<StructureSection load='4hj2' size='340' side='right'caption='[[4hj2]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4hj2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HJ2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HJ2 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LZ6:L-GAMMA-GLUTAMYL-S-(2-{[4-(3-CARBOXYPROPYL)PHENYL](2-CHLOROETHYL)AMINO}ETHYL)-L-CYSTEINYLGLYCINE'>LZ6</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hj2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hj2 OCA], [https://pdbe.org/4hj2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hj2 RCSB], [https://www.ebi.ac.uk/pdbsum/4hj2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hj2 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GSTA1_HUMAN GSTA1_HUMAN] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.<ref>PMID:20606271</ref>  


==About this Structure==
==See Also==
[[4hj2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HJ2 OCA].
*[[Glutathione S-transferase 3D structures|Glutathione S-transferase 3D structures]]
 
== References ==
==Reference==
<references/>
<references group="xtra"/><references/>
__TOC__
[[Category: Glutathione transferase]]
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Chiniadis, L.]]
[[Category: Large Structures]]
[[Category: Karpusas, M.]]
[[Category: Chiniadis L]]
[[Category: Labrou, N E.]]
[[Category: Karpusas M]]
[[Category: Alpha-beta]]
[[Category: Labrou NE]]
[[Category: Transferase]]

Latest revision as of 11:41, 1 March 2024

Crystal Structure Analysis of GSTA1-1 in complex with chlorambucil

4hj2, resolution 2.10Å

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