4e00: Difference between revisions
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== | ==Crystal structure of branched-chain alpha-ketoacid dehydrogenase kinase/3,6-dichlorobenzo[b]thiophene-2-carboxylic acid complex with ADP== | ||
<StructureSection load='4e00' size='340' side='right'caption='[[4e00]], [[Resolution|resolution]] 2.15Å' scene=''> | |||
== Structural highlights == | |||
== | <table><tr><td colspan='2'>[[4e00]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E00 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4E00 FirstGlance]. <br> | ||
[[4e00]] is a 1 chain structure with sequence from [ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0F1:3,6-DICHLORO-1-BENZOTHIOPHENE-2-CARBOXYLIC+ACID'>0F1</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4e00 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e00 OCA], [https://pdbe.org/4e00 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4e00 RCSB], [https://www.ebi.ac.uk/pdbsum/4e00 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4e00 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/BCKD_RAT BCKD_RAT] Catalyzes the phosphorylation and inactivation of the branched-chain alpha-ketoacid dehydrogenase complex, the key regulatory enzyme of the valine, leucine and isoleucine catabolic pathways. Key enzyme that regulate the activity state of the BCKD complex. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
[[Category: Chuang | [[Category: Chuang DT]] | ||
[[Category: Chuang | [[Category: Chuang JL]] | ||
[[Category: Gui | [[Category: Gui WJ]] | ||
[[Category: Li | [[Category: Li J]] | ||
[[Category: Tso | [[Category: Tso SC]] | ||
[[Category: Wynn | [[Category: Wynn RM]] | ||
Latest revision as of 11:01, 1 March 2024
Crystal structure of branched-chain alpha-ketoacid dehydrogenase kinase/3,6-dichlorobenzo[b]thiophene-2-carboxylic acid complex with ADP
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