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{{STRUCTURE_3ibw|  PDB=3ibw  |  SCENE=  }}
===Crystal Structure of the ACT domain from GTP pyrophosphokinase of Chlorobium tepidum. Northeast Structural Genomics Consortium Target CtR148A===


==Function==
==Crystal Structure of the ACT domain from GTP pyrophosphokinase of Chlorobium tepidum. Northeast Structural Genomics Consortium Target CtR148A==
[[http://www.uniprot.org/uniprot/Q8KC80_CHLTE Q8KC80_CHLTE]] In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity).[RuleBase:RU003847]  
<StructureSection load='3ibw' size='340' side='right'caption='[[3ibw]], [[Resolution|resolution]] 1.93&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[3ibw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Chlorobaculum_tepidum Chlorobaculum tepidum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IBW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IBW FirstGlance]. <br>
[[3ibw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Chlorobaculum_tepidum Chlorobaculum tepidum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IBW OCA].  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.93&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ibw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ibw OCA], [https://pdbe.org/3ibw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ibw RCSB], [https://www.ebi.ac.uk/pdbsum/3ibw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ibw ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q8KC80_CHLTE Q8KC80_CHLTE] In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity).[RuleBase:RU003847]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ib/3ibw_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ibw ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Chlorobaculum tepidum]]
[[Category: Chlorobaculum tepidum]]
[[Category: GTP diphosphokinase]]
[[Category: Large Structures]]
[[Category: Acton, T B.]]
[[Category: Acton TB]]
[[Category: Ciccosanti,C.]]
[[Category: Ciccosanti C]]
[[Category: Everett, J K.]]
[[Category: Everett JK]]
[[Category: Hunt,J F.]]
[[Category: Hunt JF]]
[[Category: Janjua,J.]]
[[Category: Janjua J]]
[[Category: Montelione, G T.]]
[[Category: Montelione GT]]
[[Category: NESG, Northeast Structural Genomics Consortium.]]
[[Category: Nair R]]
[[Category: Nair, R.]]
[[Category: Rost B]]
[[Category: Rost, B.]]
[[Category: Seetharaman J]]
[[Category: Seetharaman, J.]]
[[Category: Su M]]
[[Category: Su, M.]]
[[Category: Tong L]]
[[Category: Tong,L.]]
[[Category: Vorobiev S]]
[[Category: Vorobiev, S.]]
[[Category: Wang H]]
[[Category: Wang,H.]]
[[Category: Xiao R]]
[[Category: Xiao,R.]]
[[Category: Act domain]]
[[Category: Ctr148a]]
[[Category: Gtp pyrophosphokinase]]
[[Category: Kinase]]
[[Category: Nesg]]
[[Category: Northeast structural genomics consortium]]
[[Category: Protein structure initiative]]
[[Category: Psi-2]]
[[Category: Structural genomic]]
[[Category: Transferase]]
Retrieved from "https://proteopedia.org/3ibw"