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{{STRUCTURE_3bpw|  PDB=3bpw  |  SCENE=  }}
===Crystal Structure of P. falciparum Orotidine 5'-monophosphate Decarboxylase Complexed with XMP===


==About this Structure==
==Crystal Structure of P. falciparum Orotidine 5'-monophosphate Decarboxylase Complexed with XMP==
[[3bpw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BPW OCA].  
<StructureSection load='3bpw' size='340' side='right'caption='[[3bpw]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
[[Category: Orotidine-5'-phosphate decarboxylase]]
== Structural highlights ==
<table><tr><td colspan='2'>[[3bpw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BPW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BPW FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=XMP:XANTHOSINE-5-MONOPHOSPHATE'>XMP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bpw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bpw OCA], [https://pdbe.org/3bpw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bpw RCSB], [https://www.ebi.ac.uk/pdbsum/3bpw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bpw ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q8IJH3_PLAF7 Q8IJH3_PLAF7]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bp/3bpw_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3bpw ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Plasmodium falciparum]]
[[Category: Plasmodium falciparum]]
[[Category: Lau, W.]]
[[Category: Lau W]]
[[Category: Liu, Y.]]
[[Category: Liu Y]]
[[Category: Pai, E F.]]
[[Category: Pai EF]]
[[Category: Lyase]]
[[Category: Orotidine 5'-monophosphate decarboxylase]]
[[Category: P. falciparum]]
[[Category: Pyrimidine biosynthesis]]
[[Category: Xmp]]
Retrieved from "https://proteopedia.org/3bpw"