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{{STRUCTURE_3khj|  PDB=3khj  |  SCENE=  }}
===C. parvum inosine monophosphate dehydrogenase bound by inhibitor C64===
{{ABSTRACT_PUBMED_20052976}}


==About this Structure==
==C. parvum inosine monophosphate dehydrogenase bound by inhibitor C64==
[[3khj]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Cryptosporidium_parvum Cryptosporidium parvum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KHJ OCA].  
<StructureSection load='3khj' size='340' side='right'caption='[[3khj]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3khj]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptosporidium_parvum_Iowa_II Cryptosporidium parvum Iowa II]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KHJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KHJ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=C64:N-(4-BROMOPHENYL)-2-[2-(1,3-THIAZOL-2-YL)-1H-BENZIMIDAZOL-1-YL]ACETAMIDE'>C64</scene>, <scene name='pdbligand=IMP:INOSINIC+ACID'>IMP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3khj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3khj OCA], [https://pdbe.org/3khj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3khj RCSB], [https://www.ebi.ac.uk/pdbsum/3khj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3khj ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q5CPK7_CRYPI Q5CPK7_CRYPI]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kh/3khj_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3khj ConSurf].
<div style="clear:both"></div>


==Reference==
==See Also==
<ref group="xtra">PMID:020052976</ref><references group="xtra"/><references/>
*[[Inosine monophosphate dehydrogenase 3D structures|Inosine monophosphate dehydrogenase 3D structures]]
[[Category: Cryptosporidium parvum]]
__TOC__
[[Category: IMP dehydrogenase]]
</StructureSection>
[[Category: Hedstrom, L K.]]
[[Category: Cryptosporidium parvum Iowa II]]
[[Category: MacPherson, I S.]]
[[Category: Large Structures]]
[[Category: Enzyme-inhibitor complex]]
[[Category: Hedstrom LK]]
[[Category: Oxidoreductase]]
[[Category: MacPherson IS]]
Retrieved from "https://proteopedia.org/3khj"