3kz3: Difference between revisions

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{{STRUCTURE_3kz3|  PDB=3kz3  |  SCENE=  }}
===A structure of a lambda repressor fragment mutant===
{{ABSTRACT_PUBMED_20138892}}


==Function==
==A structure of a lambda repressor fragment mutant==
[[http://www.uniprot.org/uniprot/RPC1_LAMBD RPC1_LAMBD]] Repressor protein CI allows phage lambda to reside inactively in the chromosome of its host bacterium. This lysogenic state is maintained by binding of regulatory protein CI to the OR and OL operators, preventing transcription of proteins necessary for lytic development.  
<StructureSection load='3kz3' size='340' side='right'caption='[[3kz3]], [[Resolution|resolution]] 1.64&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[3kz3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_Lambda Escherichia virus Lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KZ3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KZ3 FirstGlance]. <br>
[[3kz3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_lambda Enterobacteria phage lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KZ3 OCA].  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.64&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kz3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kz3 OCA], [https://pdbe.org/3kz3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kz3 RCSB], [https://www.ebi.ac.uk/pdbsum/3kz3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kz3 ProSAT]</span></td></tr>
==Reference==
</table>
<ref group="xtra">PMID:020138892</ref><references group="xtra"/><references/>
== Function ==
[[Category: Enterobacteria phage lambda]]
[https://www.uniprot.org/uniprot/RPC1_LAMBD RPC1_LAMBD] Repressor protein CI allows phage lambda to reside inactively in the chromosome of its host bacterium. This lysogenic state is maintained by binding of regulatory protein CI to the OR and OL operators, preventing transcription of proteins necessary for lytic development.
[[Category: Gao, Y.]]
== Evolutionary Conservation ==
[[Category: Gruebele, M.]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: Liu, F.]]
Check<jmol>
[[Category: Dna-binding]]
  <jmolCheckbox>
[[Category: Five helix bundle]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kz/3kz3_consurf.spt"</scriptWhenChecked>
[[Category: Repressor]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Transcription]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Transcription regulation]]
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3kz3 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Escherichia virus Lambda]]
[[Category: Large Structures]]
[[Category: Gao Y]]
[[Category: Gruebele M]]
[[Category: Liu F]]

Latest revision as of 10:18, 21 February 2024

A structure of a lambda repressor fragment mutant

3kz3, resolution 1.64Å

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