3l43: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
 
(6 intermediate revisions by the same user not shown)
Line 1: Line 1:
{{STRUCTURE_3l43|  PDB=3l43  |  SCENE=  }}
===Crystal structure of the dynamin 3 GTPase domain bound with GDP===
{{ABSTRACT_PUBMED_020428112}}


==Function==
==Crystal structure of the dynamin 3 GTPase domain bound with GDP==
[[http://www.uniprot.org/uniprot/DYN3_HUMAN DYN3_HUMAN]] Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes, in particular endocytosis (By similarity).  
<StructureSection load='3l43' size='340' side='right'caption='[[3l43]], [[Resolution|resolution]] 2.27&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3l43]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L43 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3L43 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.27&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3l43 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l43 OCA], [https://pdbe.org/3l43 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3l43 RCSB], [https://www.ebi.ac.uk/pdbsum/3l43 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3l43 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DYN3_HUMAN DYN3_HUMAN] Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes, in particular endocytosis (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l4/3l43_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3l43 ConSurf].
<div style="clear:both"></div>


==About this Structure==
==See Also==
[[3l43]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L43 OCA].
*[[Bromodomain-containing protein 3D structures|Bromodomain-containing protein 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:020428112</ref><references group="xtra"/><references/>
[[Category: Dynamin GTPase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C H.]]
[[Category: Large Structures]]
[[Category: Bochkarev, A.]]
[[Category: Arrowsmith CH]]
[[Category: Bountra, C.]]
[[Category: Bochkarev A]]
[[Category: Crombet, L.]]
[[Category: Bountra C]]
[[Category: Edwards, A M.]]
[[Category: Crombet L]]
[[Category: Guan, X.]]
[[Category: Edwards AM]]
[[Category: Nedyalkova, L.]]
[[Category: Guan X]]
[[Category: Park, H.]]
[[Category: Nedyalkova L]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Park H]]
[[Category: Tempel, W.]]
[[Category: Tempel W]]
[[Category: Tong, Y.]]
[[Category: Tong Y]]
[[Category: Weigelt, J.]]
[[Category: Weigelt J]]
[[Category: Yang, S.]]
[[Category: Yang S]]
[[Category: Cytoskeleton]]
[[Category: Endocytosis]]
[[Category: Gtp-binding]]
[[Category: Hydrolase]]
[[Category: Microtubule]]
[[Category: Motor protein]]
[[Category: Nucleotide-binding]]
[[Category: Phosphoprotein]]
[[Category: Sgc]]
[[Category: Structural genomics consortium]]
Retrieved from "https://proteopedia.org/3l43"