3l8e: Difference between revisions

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{{STRUCTURE_3l8e|  PDB=3l8e  |  SCENE=  }}
===Crystal Structure of apo form of D,D-heptose 1.7-bisphosphate phosphatase from E. Coli===
{{ABSTRACT_PUBMED_20050614}}


==Function==
==Crystal Structure of apo form of D,D-heptose 1.7-bisphosphate phosphatase from E. Coli==
[[http://www.uniprot.org/uniprot/GMHB_ECOLI GMHB_ECOLI]] Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate (HBP) by removing the phosphate group at the C-7 position. Also catalyzes the dephosphorylation of fructose-1,6-bisphosphate (Fru1,6bisP).<ref>PMID:11751812</ref> <ref>PMID:16990279</ref>
<StructureSection load='3l8e' size='340' side='right'caption='[[3l8e]], [[Resolution|resolution]] 1.64&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[3l8e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L8E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3L8E FirstGlance]. <br>
[[3l8e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L8E OCA].  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.64&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
==Reference==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3l8e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l8e OCA], [https://pdbe.org/3l8e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3l8e RCSB], [https://www.ebi.ac.uk/pdbsum/3l8e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3l8e ProSAT]</span></td></tr>
<ref group="xtra">PMID:020050614</ref><references group="xtra"/><references/>
</table>
[[Category: Escherichia coli]]
== Function ==
[[Category: Allen, K N.]]
[https://www.uniprot.org/uniprot/GMHBB_ECOLI GMHBB_ECOLI] Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate (beta-HBP) intermediate into D-glycero-beta-D-manno-heptose 1-phosphate by removing the phosphate group at the C-7 position.<ref>PMID:11751812</ref> <ref>PMID:16990279</ref> <ref>PMID:20050615</ref> <ref>PMID:31449400</ref>
[[Category: Nguyen, H.]]
== Evolutionary Conservation ==
[[Category: Peisach, E.]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: 7-bisphosphate phosphatase]]
Check<jmol>
[[Category: Carbohydrate metabolism]]
  <jmolCheckbox>
[[Category: D-glycero-d-manno-heptose-1]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l8/3l8e_consurf.spt"</scriptWhenChecked>
[[Category: Gmhb]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Had superfamily]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Hydrolase]]
  </jmolCheckbox>
[[Category: Lipopolysaccharide biosynthesis]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3l8e ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Allen KN]]
[[Category: Nguyen H]]
[[Category: Peisach E]]
Retrieved from "https://proteopedia.org/3l8e"