4el6: Difference between revisions
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== | ==Crystal structure of IPSE/alpha-1 from Schistosoma mansoni eggs== | ||
[[4el6]] is a 1 chain structure with sequence from [ | <StructureSection load='4el6' size='340' side='right'caption='[[4el6]], [[Resolution|resolution]] 1.71Å' scene=''> | ||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4el6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Schistosoma_mansoni Schistosoma mansoni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EL6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EL6 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.71Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4el6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4el6 OCA], [https://pdbe.org/4el6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4el6 RCSB], [https://www.ebi.ac.uk/pdbsum/4el6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4el6 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/Q869D4_SCHMA Q869D4_SCHMA] | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
The interleukin-4-inducing principle from Schistosoma mansoni eggs (IPSE/alpha-1) triggers the release of large amounts of interleukin-4 from human blood basophils, thus presumably playing an immunomodulatory role during schistosome infection. IPSE/alpha-1 was crystallized and a native X-ray data set was collected to 1.66 A resolution from a single crystal at 100 K using synchrotron radiation. The crystal belonged to space group P6(1) or P6(5), with one molecule per asymmetric unit. | |||
Cloning, expression, purification, crystallization and preliminary X-ray crystallographic analysis of interleukin-4-inducing principle from Schistosoma mansoni eggs (IPSE/alpha-1).,Mayerhofer H, Schramm G, Hatzopoulos GN, Mueller-Dieckmann C, Haas H, Mueller-Dieckmann J Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Jun 1;65(Pt 6):594-6. doi:, 10.1107/S1744309109015899. Epub 2009 May 22. PMID:019478439<ref>PMID:019478439</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
</div> | |||
<div class="pdbe-citations 4el6" style="background-color:#fffaf0;"></div> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Schistosoma mansoni]] | [[Category: Schistosoma mansoni]] | ||
[[Category: Bade | [[Category: Bade S]] | ||
[[Category: Barths | [[Category: Barths D]] | ||
[[Category: Blindow | [[Category: Blindow S]] | ||
[[Category: Frey | [[Category: Frey A]] | ||
[[Category: Haas | [[Category: Haas H]] | ||
[[Category: Madl | [[Category: Madl T]] | ||
[[Category: Mayerhofer | [[Category: Mayerhofer H]] | ||
[[Category: Meyer | [[Category: Meyer H]] | ||
[[Category: Mueller-Dieckmann | [[Category: Mueller-Dieckmann J]] | ||
[[Category: Sattler | [[Category: Sattler M]] | ||
[[Category: Schramm | [[Category: Schramm G]] | ||
[[Category: Tripsianes | [[Category: Tripsianes K]] | ||
Latest revision as of 10:48, 6 November 2024
Crystal structure of IPSE/alpha-1 from Schistosoma mansoni eggs
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