2eek: Difference between revisions

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New page: left|200px<br /><applet load="2eek" size="350" color="white" frame="true" align="right" spinBox="true" caption="2eek, resolution 1.85Å" /> '''Crystal structure of...
 
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[[Image:2eek.jpg|left|200px]]<br /><applet load="2eek" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2eek, resolution 1.85&Aring;" />
'''Crystal structure of Atlantic cod trypsin complexed with benzamidine'''<br />


==About this Structure==
==Crystal structure of Atlantic cod trypsin complexed with benzamidine==
2EEK is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Gadus_morhua Gadus morhua] with <scene name='pdbligand=CA:'>CA</scene>, <scene name='pdbligand=NA:'>NA</scene> and <scene name='pdbligand=BEN:'>BEN</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] Known structural/functional Sites: <scene name='pdbsite=AC1:Ca+Binding+Site+For+Residue+A+401'>AC1</scene> and <scene name='pdbsite=AC2:Ben+Binding+Site+For+Residue+A+301'>AC2</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EEK OCA].  
<StructureSection load='2eek' size='340' side='right'caption='[[2eek]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2eek]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gadus_morhua Gadus morhua]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EEK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EEK FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BEN:BENZAMIDINE'>BEN</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2eek FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2eek OCA], [https://pdbe.org/2eek PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2eek RCSB], [https://www.ebi.ac.uk/pdbsum/2eek PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2eek ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TRY1_GADMO TRY1_GADMO]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ee/2eek_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2eek ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Trypsin 3D structures|Trypsin 3D structures]]
__TOC__
</StructureSection>
[[Category: Gadus morhua]]
[[Category: Gadus morhua]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Trypsin]]
[[Category: Iyaguchi D]]
[[Category: Iyaguchi, D.]]
[[Category: Toyota E]]
[[Category: Toyota, E.]]
[[Category: BEN]]
[[Category: CA]]
[[Category: NA]]
[[Category: benzamidine inhibited]]
[[Category: hydrolase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:09:17 2008''

Latest revision as of 09:05, 6 November 2024

Crystal structure of Atlantic cod trypsin complexed with benzamidine

2eek, resolution 1.85Å

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