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{{STRUCTURE_3loc|  PDB=3loc  |  SCENE=  }}
===Crystal structure of putative transcriptional regulator ycdc===


==Function==
==Crystal structure of putative transcriptional regulator ycdc==
[[http://www.uniprot.org/uniprot/RUTR_ECOLI RUTR_ECOLI]] Master transcription regulator which represses the degradation of pyrimidines (rutABCDEFG) and purines (gcl operon) for maintenance of metabolic balance between pyrimidines and purines. It also regulates the synthesis of pyrimidine nucleotides and arginine from glutamine (carAB) and the supply of glutamate (gadABWX).<ref>PMID:16540542</ref> <ref>PMID:17919280</ref>
<StructureSection load='3loc' size='340' side='right'caption='[[3loc]]' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1pb6 1pb6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LOC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LOC FirstGlance]. <br>
[[3loc]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1pb6 1pb6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LOC OCA].  
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3loc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3loc OCA], [https://pdbe.org/3loc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3loc RCSB], [https://www.ebi.ac.uk/pdbsum/3loc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3loc ProSAT]</span></td></tr>
 
</table>
==Reference==
== Evolutionary Conservation ==
<references group="xtra"/><references/>
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: Escherichia coli]]
Check<jmol>
[[Category: Almo, S C.]]
  <jmolCheckbox>
[[Category: Burley, S K.]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lo/3loc_consurf.spt"</scriptWhenChecked>
[[Category: Knapik, A A.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Mennella, V.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Minor, W.]]
  </jmolCheckbox>
[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3loc ConSurf].
[[Category: Patskovsky, Y V.]]
<div style="clear:both"></div>
[[Category: Dimer]]
__TOC__
[[Category: Dna-binding]]
</StructureSection>
[[Category: Helix-turn-helix]]
[[Category: Large Structures]]
[[Category: New york sgx research center for structural genomic]]
[[Category: Almo SC]]
[[Category: Nysgxrc]]
[[Category: Burley SK]]
[[Category: Protein structure initiative]]
[[Category: Knapik AA]]
[[Category: Psi]]
[[Category: Mennella V]]
[[Category: Putative transcriptional regulator]]
[[Category: Minor W]]
[[Category: Repressor]]
[[Category: Patskovsky YV]]
[[Category: Structural genomic]]
[[Category: Transcription]]
[[Category: Transcription regulation]]
[[Category: Uracil]]
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