4k21: Difference between revisions
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New page: '''Unreleased structure''' The entry 4k21 is ON HOLD Authors: Bezerra, G.A., Moura, T.R., Viertlmayr, R., Delatorre, P., Rocha, B.A.M., Nagano, C.S., Gruber, K., Cavada, B.S. Descripti... |
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==Crystal structure of Canavalia boliviana lectin in complex with Xman== | |||
<StructureSection load='4k21' size='340' side='right'caption='[[4k21]], [[Resolution|resolution]] 1.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4k21]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Canavalia_boliviana Canavalia boliviana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K21 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K21 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=XMM:(2R,3S,4S,5S,6R)-2-(5-BROMO-4-CHLORO-1H-INDOL-3-YLOXY)-TETRAHYDRO-6-(HYDROXYMETHYL)-2H-PYRAN-3,4,5-TRIOL'>XMM</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k21 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k21 OCA], [https://pdbe.org/4k21 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k21 RCSB], [https://www.ebi.ac.uk/pdbsum/4k21 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k21 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/LECA_CANBL LECA_CANBL] D-mannose/D-glucose-binding lectin (PubMed:24865454). Has anti-inflammatory activity in animal models when applied intravenously (PubMed:24865454). Has antinociceptive activity in mice when applied intravenously (PubMed:19705102).<ref>PMID:19705102</ref> <ref>PMID:24865454</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Canavalia boliviana]] | |||
[[Category: Large Structures]] | |||
[[Category: Bezerra GA]] | |||
[[Category: Cavada BS]] | |||
[[Category: Delatorre P]] | |||
[[Category: Gruber K]] | |||
[[Category: Moura TR]] | |||
[[Category: Nagano CS]] | |||
[[Category: Rocha BAM]] | |||
[[Category: Viertlmayr R]] | |||