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{{STRUCTURE_3nav|  PDB=3nav  |  SCENE=  }}
===Crystal structure of an alpha subunit of tryptophan synthase from Vibrio cholerae O1 biovar El Tor str. N16961===


==Function==
==Crystal structure of an alpha subunit of tryptophan synthase from Vibrio cholerae O1 biovar El Tor str. N16961==
[[http://www.uniprot.org/uniprot/TRPA_VIBCM TRPA_VIBCM]] The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate (By similarity).  
<StructureSection load='3nav' size='340' side='right'caption='[[3nav]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3nav]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_cholerae_O1_biovar_El_Tor_str._N16961 Vibrio cholerae O1 biovar El Tor str. N16961]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NAV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NAV FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nav FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nav OCA], [https://pdbe.org/3nav PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nav RCSB], [https://www.ebi.ac.uk/pdbsum/3nav PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nav ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TRPA_VIBCH TRPA_VIBCH] The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.[HAMAP-Rule:MF_00131]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/na/3nav_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3nav ConSurf].
<div style="clear:both"></div>


==About this Structure==
==See Also==
[[3nav]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_cholerae_o1_biovar_el_tor Vibrio cholerae o1 biovar el tor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NAV OCA].
*[[Tryptophan synthase 3D structures|Tryptophan synthase 3D structures]]
[[Category: Tryptophan synthase]]
__TOC__
[[Category: Vibrio cholerae o1 biovar el tor]]
</StructureSection>
[[Category: Anderson, A.]]
[[Category: Large Structures]]
[[Category: Csgid]]
[[Category: Vibrio cholerae O1 biovar El Tor str. N16961]]
[[Category: Joachimiak, A.]]
[[Category: Anderson A]]
[[Category: Kwon, K.]]
[[Category: Joachimiak A]]
[[Category: Makowska-Grzyska, M.]]
[[Category: Kwon K]]
[[Category: Nocek, B.]]
[[Category: Makowska-Grzyska M]]
[[Category: Alpha subunit]]
[[Category: Nocek B]]
[[Category: Center for structural genomics of infectious disease]]
[[Category: Csgid]]
[[Category: Lyase]]
[[Category: Structural genomic]]
[[Category: Tryptophan synthase]]
Retrieved from "https://proteopedia.org/3nav"