3mxb: Difference between revisions
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== | ==Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus== | ||
[[3mxb]] is a 8 chain structure with sequence from [ | <StructureSection load='3mxb' size='340' side='right'caption='[[3mxb]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
== Structural highlights == | |||
== | <table><tr><td colspan='2'>[[3mxb]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Chlamydomonas_reinhardtii Chlamydomonas reinhardtii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MXB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MXB FirstGlance]. <br> | ||
< | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mxb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mxb OCA], [https://pdbe.org/3mxb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mxb RCSB], [https://www.ebi.ac.uk/pdbsum/3mxb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mxb ProSAT]</span></td></tr> | |||
</table> | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mx/3mxb_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3mxb ConSurf]. | |||
<div style="clear:both"></div> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Chlamydomonas reinhardtii]] | [[Category: Chlamydomonas reinhardtii]] | ||
[[Category: Coloma | [[Category: Large Structures]] | ||
[[Category: Montoya | [[Category: Coloma J]] | ||
[[Category: Munoz | [[Category: Montoya G]] | ||
[[Category: Prieto | [[Category: Munoz IG]] | ||
[[Category: Subramanian | [[Category: Prieto J]] | ||
[[Category: Subramanian S]] | |||
Latest revision as of 10:27, 21 February 2024
Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus
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