4k5b: Difference between revisions
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New page: '''Unreleased structure''' The entry 4k5b is ON HOLD Authors: Schilling, J., Schoeppe, J., Sauer, E. Description: First crystal structure of anti-apoptotic BCL-W in its closed conforma... |
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==Co-crystallization with conformation-specific designed ankyrin repeat proteins explains the conformational flexibility of BCL-W== | |||
<StructureSection load='4k5b' size='340' side='right'caption='[[4k5b]], [[Resolution|resolution]] 1.85Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4k5b]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K5B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K5B FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k5b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k5b OCA], [https://pdbe.org/4k5b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k5b RCSB], [https://www.ebi.ac.uk/pdbsum/4k5b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k5b ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/B2CL2_BOVIN B2CL2_BOVIN] Promotes cell survival. Blocks dexamethasone-induced apoptosis. Mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX (By similarity). | |||
==See Also== | |||
*[[B-cell lymphoma proteins 3D structures|B-cell lymphoma proteins 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Bos taurus]] | |||
[[Category: Escherichia coli]] | |||
[[Category: Large Structures]] | |||
[[Category: Plueckthun A]] | |||
[[Category: Sauer E]] | |||
[[Category: Schilling J]] | |||
[[Category: Schoeppe J]] | |||
