4k8l: Difference between revisions

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~~'''Unreleased structure'''~~

~~The entry~~ 4k8l ~~is ON HOLD~~

==Crystal structure of a putative 4-hydroxyproline epimerase/3-hydroxyproline dehydratse from the soil bacterium ochrobacterium anthropi, target efi-506495, disordered loops==

~~Authors~~: ~~Vetting, M~~.W.~~, Toro, R~~.~~, Bhosle, R~~.~~, Al Obaidi, N~~.F.~~, Morisco, L~~.L.~~, Wasserman, S~~.R., ~~Sojitra, S~~.~~, Stead, M, Washington, E~~.~~, Scott Glen, A~~., ~~Chowdhury, S~~. ~~, Evens, B~~.~~, Hammonds, J~~., ~~Hillerich, B~~., ~~Love, J~~.~~, Seidel, R~~.D., ~~Imker, H~~.J., ~~Gerlt, J~~.A.~~, Almo, S~~.C.~~, Enzyme Function Initiative~~ (~~EFI~~)

== Structural highlights ==

<table><tr><td colspan='2'>[[4k8l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Brucella_anthropi_ATCC_49188 Brucella anthropi ATCC 49188]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K8L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K8L FirstGlance]. <br>

~~Description: CRYSTAL STRUCTURE OF A PUTATIVE~~ 4-~~HYDROXYPROLINE EPIMERASE/3~~-~~HYDROXYPROLINE DEHYDRATSE FROM THE SOIL BACTERIUM OCHROBACTERIUM ANTHROPI, TARGET EFI~~-~~506495~~, ~~DISORDERED LOOPS~~

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k8l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k8l OCA], [https://pdbe.org/4k8l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k8l RCSB], [https://www.ebi.ac.uk/pdbsum/4k8l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k8l ProSAT]</span></td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/4HPE1_BRUA4 4HPE1_BRUA4] Catalyzes the epimerization of trans-4-hydroxy-L-proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp) in vitro, albeit with low efficiency. The physiological substrate may be different. Displays no proline racemase activity.<ref>PMID:24980702</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Brucella anthropi ATCC 49188]]

[[Category: Large Structures]]

[[Category: Al Obaidi NF]]

[[Category: Almo SC]]

[[Category: Bhosle R]]

[[Category: Chowdhury S]]

[[Category: Evens B]]

[[Category: Gerlt JA]]

[[Category: Hammonds J]]

[[Category: Hillerich B]]

[[Category: Imker HJ]]

[[Category: Love J]]

[[Category: Morisco LL]]

[[Category: Scott Glen A]]

[[Category: Seidel RD]]

[[Category: Sojitra S]]

[[Category: Stead M]]

[[Category: Toro R]]

[[Category: Vetting MW]]

[[Category: Washington E]]

[[Category: Wasserman SR]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 4k8l is ON HOLD
+==Crystal structure of a putative 4-hydroxyproline epimerase/3-hydroxyproline dehydratse from the soil bacterium ochrobacterium anthropi, target efi-506495, disordered loops==
+<StructureSection load='4k8l' size='340' side='right'caption='[[4k8l]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-Authors: Vetting, M.W., Toro, R., Bhosle, R., Al Obaidi, N.F., Morisco, L.L., Wasserman, S.R., Sojitra, S., Stead, M, Washington, E., Scott Glen, A., Chowdhury, S. , Evens, B., Hammonds, J., Hillerich, B., Love, J., Seidel, R.D., Imker, H.J., Gerlt, J.A., Almo, S.C., Enzyme Function Initiative (EFI)
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4k8l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Brucella_anthropi_ATCC_49188 Brucella anthropi ATCC 49188]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K8L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K8L FirstGlance]. <br>
-Description: CRYSTAL STRUCTURE OF A PUTATIVE 4-HYDROXYPROLINE EPIMERASE/3-HYDROXYPROLINE DEHYDRATSE FROM THE SOIL BACTERIUM OCHROBACTERIUM ANTHROPI, TARGET EFI-506495, DISORDERED LOOPS
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k8l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k8l OCA], [https://pdbe.org/4k8l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k8l RCSB], [https://www.ebi.ac.uk/pdbsum/4k8l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k8l ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/4HPE1_BRUA4 4HPE1_BRUA4] Catalyzes the epimerization of trans-4-hydroxy-L-proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp) in vitro, albeit with low efficiency. The physiological substrate may be different. Displays no proline racemase activity.<ref>PMID:24980702</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Brucella anthropi ATCC 49188]]
+[[Category: Large Structures]]
+[[Category: Al Obaidi NF]]
+[[Category: Almo SC]]
+[[Category: Bhosle R]]
+[[Category: Chowdhury S]]
+[[Category: Evens B]]
+[[Category: Gerlt JA]]
+[[Category: Hammonds J]]
+[[Category: Hillerich B]]
+[[Category: Imker HJ]]
+[[Category: Love J]]
+[[Category: Morisco LL]]
+[[Category: Scott Glen A]]
+[[Category: Seidel RD]]
+[[Category: Sojitra S]]
+[[Category: Stead M]]
+[[Category: Toro R]]
+[[Category: Vetting MW]]
+[[Category: Washington E]]
+[[Category: Wasserman SR]]