4e9a: Difference between revisions
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== | ==Structure of Peptide Deformylase form Helicobacter Pylori in complex with inhibitor== | ||
[[http://www.uniprot.org/uniprot/Q672W7_HELPX Q672W7_HELPX | <StructureSection load='4e9a' size='340' side='right'caption='[[4e9a]], [[Resolution|resolution]] 1.66Å' scene=''> | ||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4e9a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori Helicobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E9A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4E9A FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.662Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=QAP:2-PHENYLETHYL+(2E)-3-(3,4-DIHYDROXYPHENYL)PROP-2-ENOATE'>QAP</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4e9a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e9a OCA], [https://pdbe.org/4e9a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4e9a RCSB], [https://www.ebi.ac.uk/pdbsum/4e9a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4e9a ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/Q672W7_HELPX Q672W7_HELPX] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).[HAMAP-Rule:MF_00163] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Helicobacter pylori]] | [[Category: Helicobacter pylori]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Cui | [[Category: Cui K]] | ||
[[Category: Huang | [[Category: Huang J]] | ||
[[Category: Lu | [[Category: Lu W]] | ||
[[Category: Zhu | [[Category: Zhu L]] | ||
Latest revision as of 13:46, 8 November 2023
Structure of Peptide Deformylase form Helicobacter Pylori in complex with inhibitor
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