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{{STRUCTURE_3nxc|  PDB=3nxc  |  SCENE=  }}
===Molecular mechanism by which the Escherichia coli nucleoid occlusion factor, SlmA, keeps cytokinesis in check===
{{ABSTRACT_PUBMED_21113127}}


==About this Structure==
==Molecular mechanism by which the Escherichia coli nucleoid occlusion factor, SlmA, keeps cytokinesis in check==
[[3nxc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NXC OCA].  
<StructureSection load='3nxc' size='340' side='right'caption='[[3nxc]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
 
== Structural highlights ==
==Reference==
<table><tr><td colspan='2'>[[3nxc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NXC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NXC FirstGlance]. <br>
<ref group="xtra">PMID:021113127</ref><references group="xtra"/><references/>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
[[Category: Escherichia coli]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nxc OCA], [https://pdbe.org/3nxc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nxc RCSB], [https://www.ebi.ac.uk/pdbsum/3nxc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nxc ProSAT]</span></td></tr>
[[Category: Schumacher, M A.]]
</table>
[[Category: Tonthat, N K.]]
== Function ==
[[Category: Cell division]]
[https://www.uniprot.org/uniprot/SLMA_ECOLI SLMA_ECOLI] Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.[HAMAP-Rule:MF_01839]<ref>PMID:15916962</ref> <ref>PMID:21113127</ref> <ref>PMID:21321206</ref>
[[Category: Dna binding protein]]
== References ==
[[Category: Nucleoid occlusion]]
<references/>
[[Category: Tetr family member]]
__TOC__
</StructureSection>
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Schumacher MA]]
[[Category: Tonthat NK]]
Retrieved from "https://proteopedia.org/3nxc"