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{{STRUCTURE_3o02|  PDB=3o02  |  SCENE=  }}
===The Crystal Structure of the Salmonella Type III Secretion System Tip Protein SipD in Complex with Chenodeoxycholate===
{{ABSTRACT_PUBMED_21031487}}


==Function==
==The Crystal Structure of the Salmonella Type III Secretion System Tip Protein SipD in Complex with Chenodeoxycholate==
[[http://www.uniprot.org/uniprot/SIPD_SALTY SIPD_SALTY]] Required for translocation of effector proteins via the type III secretion system SPI-1, which is essential for an efficient bacterial internalization. Probably acts by modulating the secretion of SipA, SipB, and SipC.<ref>PMID:8522512</ref> <ref>PMID:9194702</ref>
<StructureSection load='3o02' size='340' side='right'caption='[[3o02]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[3o02]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O02 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3O02 FirstGlance]. <br>
[[3o02]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica Salmonella enterica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O02 OCA].  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=JN3:CHENODEOXYCHOLIC+ACID'>JN3</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
==Reference==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3o02 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o02 OCA], [https://pdbe.org/3o02 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3o02 RCSB], [https://www.ebi.ac.uk/pdbsum/3o02 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3o02 ProSAT]</span></td></tr>
<ref group="xtra">PMID:021031487</ref><references group="xtra"/><references/>
</table>
[[Category: Salmonella enterica]]
== Function ==
[[Category: Battaile, K P.]]
[https://www.uniprot.org/uniprot/SIPD_SALTY SIPD_SALTY] Required for translocation of effector proteins via the type III secretion system SPI-1, which is essential for an efficient bacterial internalization. Probably acts by modulating the secretion of SipA, SipB, and SipC.<ref>PMID:8522512</ref> <ref>PMID:9194702</ref>
[[Category: Chatterjee, S.]]
== References ==
[[Category: DeGuzman, R N.]]
<references/>
[[Category: Lovell, S.]]
__TOC__
[[Category: Nordhues, B A.]]
</StructureSection>
[[Category: Zhong, D.]]
[[Category: Large Structures]]
[[Category: Bacterial needle tip protein]]
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
[[Category: Cell invasion]]
[[Category: Battaile KP]]
[[Category: Coiled-coil]]
[[Category: Chatterjee S]]
[[Category: Prgi]]
[[Category: DeGuzman RN]]
[[Category: Sipb]]
[[Category: Lovell S]]
[[Category: Sipc]]
[[Category: Nordhues BA]]
[[Category: Zhong D]]
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