3j3r: Difference between revisions
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==Structural dynamics of the MecA-ClpC complex revealed by cryo-EM== | |||
<SX load='3j3r' size='340' side='right' viewer='molstar' caption='[[3j3r]], [[Resolution|resolution]] 9.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3j3r]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._subtilis_str._168 Bacillus subtilis subsp. subtilis str. 168]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J3R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3J3R FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 9.4Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3j3r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j3r OCA], [https://pdbe.org/3j3r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3j3r RCSB], [https://www.ebi.ac.uk/pdbsum/3j3r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3j3r ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/MECA1_BACSU MECA1_BACSU] Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC.<ref>PMID:12598648</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</SX> | |||
[[Category: Bacillus subtilis subsp. subtilis str. 168]] | |||
[[Category: Large Structures]] | |||
[[Category: Gao N]] | |||
[[Category: Lei J]] | |||
[[Category: Li N]] | |||
[[Category: Liu J]] | |||
[[Category: Mei Z]] | |||
[[Category: Qi Y]] | |||
[[Category: Shi Y]] | |||
[[Category: Wang F]] | |||
[[Category: Xu Y]] | |||
Latest revision as of 08:28, 20 March 2024
Structural dynamics of the MecA-ClpC complex revealed by cryo-EM
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