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{{STRUCTURE_3opt|  PDB=3opt  |  SCENE=  }}
===Crystal structure of the Rph1 catalytic core with a-ketoglutarate===
{{ABSTRACT_PUBMED_21067515}}


==Function==
==Crystal structure of the Rph1 catalytic core with a-ketoglutarate==
[[http://www.uniprot.org/uniprot/RPH1_YEAST RPH1_YEAST]] Transcriptional repressor of photolyase PHR1. Recognizes and binds the sequence AG(4) in the upstream repressing sequence of PHR1. Derepresses PHR1 transcription when phosphorylated.<ref>PMID:10523651</ref> <ref>PMID:11809875</ref>
<StructureSection load='3opt' size='340' side='right'caption='[[3opt]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[3opt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OPT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OPT FirstGlance]. <br>
[[3opt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OPT OCA].  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AKG:2-OXOGLUTARIC+ACID'>AKG</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
==Reference==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3opt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3opt OCA], [https://pdbe.org/3opt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3opt RCSB], [https://www.ebi.ac.uk/pdbsum/3opt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3opt ProSAT]</span></td></tr>
<ref group="xtra">PMID:021067515</ref><references group="xtra"/><references/>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RPH1_YEAST RPH1_YEAST] Transcriptional repressor of photolyase PHR1. Recognizes and binds the sequence AG(4) in the upstream repressing sequence of PHR1. Derepresses PHR1 transcription when phosphorylated.<ref>PMID:10523651</ref> <ref>PMID:11809875</ref>  
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Chang, Y.]]
[[Category: Chang Y]]
[[Category: Ding, J.]]
[[Category: Ding J]]
[[Category: Tong, X.]]
[[Category: Tong X]]
[[Category: Wu, J.]]
[[Category: Wu J]]
[[Category: Zhou, J.]]
[[Category: Zhou J]]
[[Category: Catalytic core]]
[[Category: Histone demethylase]]
[[Category: Oxidoreductase]]
[[Category: Rph1]]