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[[Image:2for.jpg|left|200px]]<br /><applet load="2for" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2for, resolution 2.00&Aring;" />
'''Crystal Structure of the Shigella flexneri Farnesyl Pyrophosphate Synthase Complex with an Isopentenyl Pyrophosphate'''<br />


==About this Structure==
==Crystal Structure of the Shigella flexneri Farnesyl Pyrophosphate Synthase Complex with an Isopentenyl Pyrophosphate==
2FOR is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Shigella_flexneri Shigella flexneri] with <scene name='pdbligand=PO4:'>PO4</scene> and <scene name='pdbligand=IPR:'>IPR</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Geranyltranstransferase Geranyltranstransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.10 2.5.1.10] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FOR OCA].  
<StructureSection load='2for' size='340' side='right'caption='[[2for]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
[[Category: Geranyltranstransferase]]
== Structural highlights ==
<table><tr><td colspan='2'>[[2for]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Shigella_flexneri Shigella flexneri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FOR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FOR FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IPR:ISOPENTYL+PYROPHOSPHATE'>IPR</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2for FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2for OCA], [https://pdbe.org/2for PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2for RCSB], [https://www.ebi.ac.uk/pdbsum/2for PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2for ProSAT], [https://www.topsan.org/Proteins/MCSG/2for TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A0H2UXE9_SHIFL A0A0H2UXE9_SHIFL]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fo/2for_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2for ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Farnesyl diphosphate synthase 3D structures|Farnesyl diphosphate synthase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Shigella flexneri]]
[[Category: Shigella flexneri]]
[[Category: Single protein]]
[[Category: Anderson WF]]
[[Category: Anderson, W F.]]
[[Category: Brunzelle JS]]
[[Category: Brunzelle, J S.]]
[[Category: Collart FR]]
[[Category: Collart, F R.]]
[[Category: Joachimiak A]]
[[Category: MCSG, Midwest Center for Structural Genomics.]]
[[Category: Minasov G]]
[[Category: Minasov, G.]]
[[Category: Shuvalova L]]
[[Category: Shuvalova, L.]]
[[Category: IPR]]
[[Category: PO4]]
[[Category: bisphosphonate; isoprenyl synthase]]
[[Category: mcsg]]
[[Category: midwest center for structural genomics]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: structural genomics]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:23:37 2008''

Latest revision as of 09:24, 14 February 2024

Crystal Structure of the Shigella flexneri Farnesyl Pyrophosphate Synthase Complex with an Isopentenyl Pyrophosphate

2for, resolution 2.00Å

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