2g1w: Difference between revisions

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[[Image:2g1w.gif|left|200px]]<br /><applet load="2g1w" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2g1w" />
'''NMR structure of the Aquifex aeolicus tmRNA pseudoknot PK1'''<br />


==Overview==
==NMR structure of the Aquifex aeolicus tmRNA pseudoknot PK1==
<StructureSection load='2g1w' size='340' side='right'caption='[[2g1w]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2g1w]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G1W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2G1W FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2g1w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g1w OCA], [https://pdbe.org/2g1w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2g1w RCSB], [https://www.ebi.ac.uk/pdbsum/2g1w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2g1w ProSAT]</span></td></tr>
</table>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
The transfer-messenger RNA (tmRNA) pseudoknot PK1 is essential for bacterial trans-translation, a ribosomal rescue mechanism. We report the solution structure of PK1 from Aquifex aeolicus, which despite an unprecedented small number of nucleotides and thus an unprecented compact size, displays a very high thermal stability. Several unusual structural features account for these properties and indicate that PK1 belongs to the class of ribosomal frameshift pseudoknots. This suggests a similarity between the mechanism of programmed ribosomal frameshifting and trans-translation.
The transfer-messenger RNA (tmRNA) pseudoknot PK1 is essential for bacterial trans-translation, a ribosomal rescue mechanism. We report the solution structure of PK1 from Aquifex aeolicus, which despite an unprecedented small number of nucleotides and thus an unprecented compact size, displays a very high thermal stability. Several unusual structural features account for these properties and indicate that PK1 belongs to the class of ribosomal frameshift pseudoknots. This suggests a similarity between the mechanism of programmed ribosomal frameshifting and trans-translation.


==About this Structure==
NMR structure of the Aquifex aeolicus tmRNA pseudoknot PK1: new insights into the recoding event of the ribosomal trans-translation.,Nonin-Lecomte S, Felden B, Dardel F Nucleic Acids Res. 2006 Apr 4;34(6):1847-53. Print 2006. PMID:16595798<ref>PMID:16595798</ref>
2G1W is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G1W OCA].


==Reference==
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
NMR structure of the Aquifex aeolicus tmRNA pseudoknot PK1: new insights into the recoding event of the ribosomal trans-translation., Nonin-Lecomte S, Felden B, Dardel F, Nucleic Acids Res. 2006 Apr 4;34(6):1847-53. Print 2006. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16595798 16595798]
</div>
[[Category: Protein complex]]
<div class="pdbe-citations 2g1w" style="background-color:#fffaf0;"></div>
[[Category: Dardel, F.]]
== References ==
[[Category: Nonin-Lecomte, S.]]
<references/>
[[Category: nmr]]
__TOC__
[[Category: pk1]]
</StructureSection>
[[Category: pseudoknot]]
[[Category: Large Structures]]
[[Category: tmrna]]
[[Category: Dardel F]]
[[Category: trans-translation]]
[[Category: Nonin-Lecomte S]]
 
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