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{{STRUCTURE_3pst|  PDB=3pst  |  SCENE=  }}
===Crystal structure of PUL and PFU(mutate) domain===


==Function==
==Crystal structure of PUL and PFU(mutate) domain==
[[http://www.uniprot.org/uniprot/DOA1_YEAST DOA1_YEAST]] Participates in the regulation of the ubiquitin conjugation pathway involving CDC48 by hindering multiubiquitination of substrates at the CDC48 chaperone. May act by preventing the interaction between CDC48 and the E4 enzyme UFD2, leading to prevent multiubiquitination of substrates and subsequent degradation. Essential for maintaining cellular ubiquitin levels.<ref>PMID:15096053</ref> <ref>PMID:8890162</ref>
<StructureSection load='3pst' size='340' side='right'caption='[[3pst]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[3pst]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PST OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PST FirstGlance]. <br>
[[3pst]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PST OCA].
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.999&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pst FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pst OCA], [https://pdbe.org/3pst PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pst RCSB], [https://www.ebi.ac.uk/pdbsum/3pst PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pst ProSAT]</span></td></tr>
==Reference==
</table>
<references group="xtra"/><references/>
== Function ==
[https://www.uniprot.org/uniprot/DOA1_YEAST DOA1_YEAST] Participates in the regulation of the ubiquitin conjugation pathway involving CDC48 by hindering multiubiquitination of substrates at the CDC48 chaperone. May act by preventing the interaction between CDC48 and the E4 enzyme UFD2, leading to prevent multiubiquitination of substrates and subsequent degradation. Essential for maintaining cellular ubiquitin levels.<ref>PMID:15096053</ref> <ref>PMID:8890162</ref>  
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Liu, Y.]]
[[Category: Liu Y]]
[[Category: Sun, J.]]
[[Category: Sun J]]
[[Category: Cdc48]]
[[Category: Nuclear protein]]
[[Category: Protein degradation]]
[[Category: Ubiquitin]]
Retrieved from "https://proteopedia.org/3pst"