3plt: Difference between revisions
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== | ==Crystal structure of Lsp1 from Saccharomyces cerevisiae== | ||
[[3plt]] is a 3 chain structure with sequence from [ | <StructureSection load='3plt' size='340' side='right'caption='[[3plt]], [[Resolution|resolution]] 2.90Å' scene=''> | ||
== Structural highlights == | |||
== | <table><tr><td colspan='2'>[[3plt]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PLT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PLT FirstGlance]. <br> | ||
< | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3plt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3plt OCA], [https://pdbe.org/3plt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3plt RCSB], [https://www.ebi.ac.uk/pdbsum/3plt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3plt ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/LSP1_YEAST LSP1_YEAST] Together with PIL1, main component of eisosomes, structures at the cell periphery underneath the plasma membrane that mark the site of endocytosis. Negative regulator of cell wall integrity (CWI) in unstressed cells, probably by inhibiting protein kinase PKH1/PHK2 activity and regulating their downstream CWI pathways PKC1-MAP kinase pathway and protein kinase YPK1 pathway. Activity may be regulated by the transient increase of sphingolipid long chain bases (LCBs) during heat stress.<ref>PMID:15016821</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
[[Category: Walther | [[Category: Walther TC]] | ||
[[Category: Ziolkowska | [[Category: Ziolkowska NE]] | ||
Latest revision as of 10:41, 21 February 2024
Crystal structure of Lsp1 from Saccharomyces cerevisiae
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