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{{STRUCTURE_3ps3|  PDB=3ps3  |  SCENE=  }}
===Crystal structure of the Escherichia Coli LPXC/LPC-053 complex===
{{ABSTRACT_PUBMED_21194954}}


==Function==
==Crystal structure of the Escherichia Coli LPXC/LPC-053 complex==
[[http://www.uniprot.org/uniprot/D5CV28_ECOKI D5CV28_ECOKI]] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity).[HAMAP-Rule:MF_00388][SAAS:SAAS004463_004_013136]  
<StructureSection load='3ps3' size='340' side='right'caption='[[3ps3]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3ps3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_IHE3034 Escherichia coli IHE3034]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PS3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PS3 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=L53:4-[4-(4-AMINOPHENYL)BUTA-1,3-DIYN-1-YL]-N-[(2S,3S)-3-HYDROXY-1-NITROSO-1-OXOBUTAN-2-YL]BENZAMIDE'>L53</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UKW:4-ETHYNYL-N-[(1S,2R)-2-HYDROXY-1-(OXOCARBAMOYL)PROPYL]BENZAMIDE'>UKW</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ps3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ps3 OCA], [https://pdbe.org/3ps3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ps3 RCSB], [https://www.ebi.ac.uk/pdbsum/3ps3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ps3 ProSAT]</span></td></tr>
</table>


==About this Structure==
==See Also==
[[3ps3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_ihe3034 Escherichia coli ihe3034]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PS3 OCA].
*[[UDP-3-O-acyl-N-acetylglucosamine deacetylase|UDP-3-O-acyl-N-acetylglucosamine deacetylase]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:021194954</ref><references group="xtra"/><references/>
[[Category: Escherichia coli IHE3034]]
[[Category: Escherichia coli ihe3034]]
[[Category: Large Structures]]
[[Category: Lee, C J]]
[[Category: Lee C-J]]
[[Category: Zhou, P.]]
[[Category: Zhou P]]
[[Category: Acyl udp-glcnac]]
[[Category: Antibiotic]]
[[Category: Baab sandwich]]
[[Category: Deacetylation]]
[[Category: Hydrolase]]
[[Category: Hydrolase-antibiotic complex]]
[[Category: Hydroxamate]]
[[Category: Lipid a biosynthesis]]
[[Category: Lipid a synthesis]]
[[Category: Lpc-053]]
[[Category: Lpxc]]

Latest revision as of 10:43, 21 February 2024

Crystal structure of the Escherichia Coli LPXC/LPC-053 complex

3ps3, resolution 2.10Å

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