4fqg: Difference between revisions

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{{STRUCTURE_4fqg|  PDB=4fqg  |  SCENE=  }}
===Crystal structure of the TCERG1 FF4-6 tandem repeat domain===
{{ABSTRACT_PUBMED_23436654}}


==Function==
==Crystal structure of the TCERG1 FF4-6 tandem repeat domain==
[[http://www.uniprot.org/uniprot/TCRG1_HUMAN TCRG1_HUMAN]] Transcription factor that binds RNA polymerase II and inhibits the elongation of transcripts from target promoters. Regulates transcription elongation in a TATA box-dependent manner. Necessary for TAT-dependent activation of the human immunodeficiency virus type 1 (HIV-1) promoter.<ref>PMID:9315662</ref> <ref>PMID:11604498</ref>
<StructureSection load='4fqg' size='340' side='right'caption='[[4fqg]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[4fqg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FQG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FQG FirstGlance]. <br>
[[4fqg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FQG OCA].
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
==Reference==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fqg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fqg OCA], [https://pdbe.org/4fqg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fqg RCSB], [https://www.ebi.ac.uk/pdbsum/4fqg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fqg ProSAT]</span></td></tr>
<references group="xtra"/><references/>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TCRG1_HUMAN TCRG1_HUMAN] Transcription factor that binds RNA polymerase II and inhibits the elongation of transcripts from target promoters. Regulates transcription elongation in a TATA box-dependent manner. Necessary for TAT-dependent activation of the human immunodeficiency virus type 1 (HIV-1) promoter.<ref>PMID:9315662</ref> <ref>PMID:11604498</ref>  
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Fan, S.]]
[[Category: Large Structures]]
[[Category: Greenleaf, A L.]]
[[Category: Fan S]]
[[Category: Lee, C J.]]
[[Category: Greenleaf AL]]
[[Category: Liu, J.]]
[[Category: Lee CJ]]
[[Category: Zhou, P.]]
[[Category: Liu J]]
[[Category: Ff domain]]
[[Category: Zhou P]]
[[Category: Pctd-binding domain]]
[[Category: Tandem repeat domain]]
[[Category: Transcription]]
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