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[[Image:2gjz.jpg|left|200px]]<br /><applet load="2gjz" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2gjz, resolution 2.65&Aring;" />
'''Structure of Catalytic Elimination Antibody 13G5 from a crystal in space group P2(1)'''<br />


==About this Structure==
==Structure of Catalytic Elimination Antibody 13G5 from a crystal in space group P2(1)==
2GJZ is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] with <scene name='pdbligand=ZN:'>ZN</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GJZ OCA].  
<StructureSection load='2gjz' size='340' side='right'caption='[[2gjz]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2gjz]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GJZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GJZ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gjz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gjz OCA], [https://pdbe.org/2gjz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gjz RCSB], [https://www.ebi.ac.uk/pdbsum/2gjz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gjz ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q65ZC0_MOUSE Q65ZC0_MOUSE]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gj/2gjz_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gjz ConSurf].
<div style="clear:both"></div>


==Reference==
==See Also==
Bifunctional catalysis of proton transfer at an antibody active site., Muller R, Debler EW, Steinmann M, Seebeck FP, Wilson IA, Hilvert D, J Am Chem Soc. 2007 Jan 24;129(3):460-1. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17226987 17226987]
*[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Protein complex]]
[[Category: Debler EW]]
[[Category: Debler, E W.]]
[[Category: Wilson IA]]
[[Category: Wilson, I A.]]
[[Category: ZN]]
[[Category: catalytic antibody]]
[[Category: elimination]]
[[Category: immunoglobulin]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:32:27 2008''

Latest revision as of 00:58, 21 November 2024

Structure of Catalytic Elimination Antibody 13G5 from a crystal in space group P2(1)

2gjz, resolution 2.65Å

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