2gm7: Difference between revisions

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[[Image:2gm7.gif|left|200px]]<br /><applet load="2gm7" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2gm7, resolution 2.800&Aring;" />
'''TenA Homolog/Thi-4 Thiaminase from Pyrobaculum Aerophilum'''<br />


==About this Structure==
==TenA Homolog/Thi-4 Thiaminase from Pyrobaculum Aerophilum==
2GM7 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Pyrobaculum_aerophilum_str._im2 Pyrobaculum aerophilum str. im2] with <scene name='pdbligand=PO4:'>PO4</scene>, <scene name='pdbligand=PE4:'>PE4</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Thiamine_pyridinylase Thiamine pyridinylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.2 2.5.1.2] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GM7 OCA].
<StructureSection load='2gm7' size='340' side='right'caption='[[2gm7]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
[[Category: Pyrobaculum aerophilum str. im2]]
== Structural highlights ==
[[Category: Single protein]]
<table><tr><td colspan='2'>[[2gm7]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrobaculum_aerophilum_str._IM2 Pyrobaculum aerophilum str. IM2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GM7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GM7 FirstGlance]. <br>
[[Category: Thiamine pyridinylase]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
[[Category: Chan, S.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PE4:2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL'>PE4</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
[[Category: Han, G W.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gm7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gm7 OCA], [https://pdbe.org/2gm7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gm7 RCSB], [https://www.ebi.ac.uk/pdbsum/2gm7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gm7 ProSAT]</span></td></tr>
[[Category: Perry, L J.]]
</table>
[[Category: Sawaya, M R.]]
== Function ==
[[Category: GOL]]
[https://www.uniprot.org/uniprot/Q8ZZM9_PYRAE Q8ZZM9_PYRAE]  
[[Category: PE4]]
== Evolutionary Conservation ==
[[Category: PO4]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: thiaminase]]
Check<jmol>
[[Category: transcription]]
  <jmolCheckbox>
 
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gm/2gm7_consurf.spt"</scriptWhenChecked>
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:33:08 2008''
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gm7 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Pyrobaculum aerophilum str. IM2]]
[[Category: Chan S]]
[[Category: Han GW]]
[[Category: Perry LJ]]
[[Category: Sawaya MR]]
Retrieved from "https://proteopedia.org/2gm7"