2lez: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
 
(6 intermediate revisions by the same user not shown)
Line 1: Line 1:
{{STRUCTURE_2lez|  PDB=2lez  |  SCENE=  }}
===Solution NMR structure of N-terminal domain of Salmonella effector protein PipB2. Northeast structural genomics consortium (NESG) target stt318a===


==Function==
==Solution NMR structure of N-terminal domain of Salmonella effector protein PipB2. Northeast structural genomics consortium (NESG) target stt318a==
[[http://www.uniprot.org/uniprot/PIPB2_SALTY PIPB2_SALTY]] Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. Involved in the reorganization of late endosome/lysosome (LE/Lys) compartments in mammalian cells. Necessary and sufficient to link kinesin-1 onto the Salmonella-containing vacuole (SCV) membrane. Required for centrifugal extension of lysosomal glycoprotein-rich membrane tubules, known as Salmonella-induced filaments (Sifs), away from the SCV and toward the cell periphery. Required for virulence, but not for intracellular survival and replication in phagocytic cells.<ref>PMID:12864852</ref> <ref>PMID:15987736</ref> <ref>PMID:16938850</ref>
<StructureSection load='2lez' size='340' side='right'caption='[[2lez]]' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[2lez]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LEZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LEZ FirstGlance]. <br>
[[2lez]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LEZ OCA].
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lez OCA], [https://pdbe.org/2lez PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lez RCSB], [https://www.ebi.ac.uk/pdbsum/2lez PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lez ProSAT]</span></td></tr>
==Reference==
</table>
<references group="xtra"/><references/>
== Function ==
[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
[https://www.uniprot.org/uniprot/PIPB2_SALTY PIPB2_SALTY] Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. Involved in the reorganization of late endosome/lysosome (LE/Lys) compartments in mammalian cells. Necessary and sufficient to link kinesin-1 onto the Salmonella-containing vacuole (SCV) membrane. Required for centrifugal extension of lysosomal glycoprotein-rich membrane tubules, known as Salmonella-induced filaments (Sifs), away from the SCV and toward the cell periphery. Required for virulence, but not for intracellular survival and replication in phagocytic cells.<ref>PMID:12864852</ref> <ref>PMID:15987736</ref> <ref>PMID:16938850</ref>  
[[Category: Arrowsmith, C.]]
== References ==
[[Category: Daniels, C.]]
<references/>
[[Category: Garcia, M.]]
__TOC__
[[Category: Houliston, S.]]
</StructureSection>
[[Category: Lemak, A.]]
[[Category: Large Structures]]
[[Category: Montelione, G T.]]
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
[[Category: NESG, Northeast Structural Genomics Consortium.]]
[[Category: Arrowsmith C]]
[[Category: Savchenko, A.]]
[[Category: Daniels C]]
[[Category: Yee, A.]]
[[Category: Garcia M]]
[[Category: Bacterial effector]]
[[Category: Houliston S]]
[[Category: Nesg]]
[[Category: Lemak A]]
[[Category: Northeast structural genomics consortium]]
[[Category: Montelione GT]]
[[Category: Signaling protein]]
[[Category: Savchenko A]]
[[Category: Structural genomic]]
[[Category: Yee A]]
[[Category: Virulence factor]]
Retrieved from "https://proteopedia.org/2lez"