3s24: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
 
(4 intermediate revisions by the same user not shown)
Line 1: Line 1:
{{STRUCTURE_3s24|  PDB=3s24  |  SCENE=  }}
===Crystal structure of human mRNA guanylyltransferase===
{{ABSTRACT_PUBMED_21636784}}


==Function==
==Crystal structure of human mRNA guanylyltransferase==
[[http://www.uniprot.org/uniprot/MCE1_HUMAN MCE1_HUMAN]] Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus.
<StructureSection load='3s24' size='340' side='right'caption='[[3s24]], [[Resolution|resolution]] 3.01&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[3s24]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S24 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S24 FirstGlance]. <br>
[[3s24]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S24 OCA].  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.0137&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
==Reference==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s24 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s24 OCA], [https://pdbe.org/3s24 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s24 RCSB], [https://www.ebi.ac.uk/pdbsum/3s24 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s24 ProSAT]</span></td></tr>
<ref group="xtra">PMID:021636784</ref><references group="xtra"/><references/>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MCE1_HUMAN MCE1_HUMAN] Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus.
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arnold, E.]]
[[Category: Large Structures]]
[[Category: Bauman, J D.]]
[[Category: Arnold E]]
[[Category: Chu, C.]]
[[Category: Bauman JD]]
[[Category: Das, K.]]
[[Category: Chu C]]
[[Category: Guan, R.]]
[[Category: Das K]]
[[Category: Montelione, G T.]]
[[Category: Guan R]]
[[Category: Qiu, W.]]
[[Category: Montelione GT]]
[[Category: Shatkin, A J.]]
[[Category: Qiu W]]
[[Category: Thyminski, J R.]]
[[Category: Shatkin AJ]]
[[Category: Capping enzyme]]
[[Category: Thyminski JR]]
[[Category: Ce]]
[[Category: Ctd]]
[[Category: Gt/dna ligase fold]]
[[Category: Gtase]]
[[Category: Hce]]
[[Category: Hydrolase]]
[[Category: M7gpppn cap]]
[[Category: Transcription factor spt5]]
[[Category: Transferase]]
Retrieved from "https://proteopedia.org/3s24"