3q0l: Difference between revisions

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{{STRUCTURE_3q0l|  PDB=3q0l  |  SCENE=  }}
===Crystal structure of the PUMILIO-homology domain from Human PUMILIO1 in complex with p38alpha NREa===
{{ABSTRACT_PUBMED_21397187}}


==Function==
==Crystal structure of the PUMILIO-homology domain from Human PUMILIO1 in complex with p38alpha NREa==
[[http://www.uniprot.org/uniprot/PUM1_HUMAN PUM1_HUMAN]] Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of mRNA targets. May be required to support proliferation and self-renewal of stem cells (By similarity).
<StructureSection load='3q0l' size='340' side='right'caption='[[3q0l]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[3q0l]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q0L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q0L FirstGlance]. <br>
[[3q0l]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q0L OCA].  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.503&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q0l OCA], [https://pdbe.org/3q0l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q0l RCSB], [https://www.ebi.ac.uk/pdbsum/3q0l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q0l ProSAT]</span></td></tr>
==Reference==
</table>
<ref group="xtra">PMID:021397187</ref><references group="xtra"/><references/>
== Function ==
[https://www.uniprot.org/uniprot/PUM1_HUMAN PUM1_HUMAN] Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of mRNA targets. May be required to support proliferation and self-renewal of stem cells (By similarity).
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Hall, T M.T.]]
[[Category: Large Structures]]
[[Category: Lu, G.]]
[[Category: Hall TMT]]
[[Category: Gene regulation]]
[[Category: Lu G]]
[[Category: Puf]]
[[Category: Pumilio-homolgy domain]]
[[Category: Rna binding]]
[[Category: Rna binding protein-rna complex]]
Retrieved from "https://proteopedia.org/3q0l"