4k1y: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
 
(6 intermediate revisions by the same user not shown)
Line 1: Line 1:
'''Unreleased structure'''


The entry 4k1y is ON HOLD  until Paper Publication
==Crystal structure of Canavalia boliviana lectin in complex with Man1-3Man-OMe==
 
<StructureSection load='4k1y' size='340' side='right'caption='[[4k1y]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
Authors: Bezerra, G.A., Viertlmayr, R., Moura, T.R., Delatorre, P., Rocha, B.A.M., Cavada, B.S., Gruber, K.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4k1y]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Canavalia_boliviana Canavalia boliviana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K1Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K1Y FirstGlance]. <br>
Description: Crystal structure of Canavalia boliviana lectin in complex with Man1-3Man-OMe
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=MMA:O1-METHYL-MANNOSE'>MMA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k1y OCA], [https://pdbe.org/4k1y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k1y RCSB], [https://www.ebi.ac.uk/pdbsum/4k1y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k1y ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/LECA_CANBL LECA_CANBL] D-mannose/D-glucose-binding lectin (PubMed:24865454). Has anti-inflammatory activity in animal models when applied intravenously (PubMed:24865454). Has antinociceptive activity in mice when applied intravenously (PubMed:19705102).<ref>PMID:19705102</ref> <ref>PMID:24865454</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Canavalia boliviana]]
[[Category: Large Structures]]
[[Category: Bezerra GA]]
[[Category: Cavada BS]]
[[Category: Delatorre P]]
[[Category: Gruber K]]
[[Category: Moura TR]]
[[Category: Rocha BAM]]
[[Category: Viertlmayr R]]