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[[Image:2h18.gif|left|200px]]<br /><applet load="2h18" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2h18, resolution 1.902&Aring;" />
'''Structure of human ADP-ribosylation factor-like 10B (ARL10B)'''<br />


==About this Structure==
==Structure of human ADP-ribosylation factor-like 10B (ARL10B)==
2H18 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=GDP:'>GDP</scene> and <scene name='pdbligand=UNX:'>UNX</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H18 OCA].  
<StructureSection load='2h18' size='340' side='right'caption='[[2h18]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2h18]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H18 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2H18 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.902&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2h18 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h18 OCA], [https://pdbe.org/2h18 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2h18 RCSB], [https://www.ebi.ac.uk/pdbsum/2h18 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2h18 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ARL8A_HUMAN ARL8A_HUMAN] May play a role in lysosomes motility. Alternatively, may play a role in chromosome segregation (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h1/2h18_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2h18 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Arrowsmith, C H.]]
[[Category: Arrowsmith CH]]
[[Category: Atanassova, A.]]
[[Category: Atanassova A]]
[[Category: Bochkarev, A.]]
[[Category: Bochkarev A]]
[[Category: Dimov, S.]]
[[Category: Dimov S]]
[[Category: Edwards, A M.]]
[[Category: Edwards AM]]
[[Category: Park, H.]]
[[Category: Park H]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Sundstrom M]]
[[Category: Sundstrom, M.]]
[[Category: Tempel W]]
[[Category: Tempel, W.]]
[[Category: Weigelt J]]
[[Category: Weigelt, J.]]
[[Category: Yaniw D]]
[[Category: Yaniw, D.]]
[[Category: GDP]]
[[Category: UNX]]
[[Category: gdp]]
[[Category: gtpase]]
[[Category: membrane trafficking]]
[[Category: sgc]]
[[Category: structural genomics]]
[[Category: structural genomics consortium]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:37:09 2008''

Latest revision as of 09:50, 30 August 2023

Structure of human ADP-ribosylation factor-like 10B (ARL10B)

2h18, resolution 1.90Å

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