4l5f: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
m Protected "4l5f" [edit=sysop:move=sysop]
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
No edit summary
 
(5 intermediate revisions by the same user not shown)
Line 1: Line 1:
'''Unreleased structure'''


The entry 4l5f is ON HOLD
==Crystal Structure of DENV1-E106 Fab bound to DENV-1 Envelope protein DIII==
<StructureSection load='4l5f' size='340' side='right'caption='[[4l5f]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4l5f]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Dengue_virus_1 Dengue virus 1] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L5F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4L5F FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4l5f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l5f OCA], [https://pdbe.org/4l5f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4l5f RCSB], [https://www.ebi.ac.uk/pdbsum/4l5f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4l5f ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q8BE40_9FLAV Q8BE40_9FLAV] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS026470_004_099774]


Authors: Edeling, M.A., Nelson, C.A., Fremont, D.H., Center for Structural Genomics of Infectious Diseases (CSGID)
==See Also==
 
*[[Antibody 3D structures|Antibody 3D structures]]
Description: Crystal Structure of DENV1-E106 Fab bound to DENV-1 Envelope protein DIII
*[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]]
*[[3D structures of non-human antibody|3D structures of non-human antibody]]
__TOC__
</StructureSection>
[[Category: Dengue virus 1]]
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Edeling MA]]
[[Category: Fremont DH]]
[[Category: Nelson CA]]
Retrieved from "https://proteopedia.org/4l5f"