4l6a: Difference between revisions

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'''Unreleased structure'''


The entry 4l6a is ON HOLD
==Structure of human mitochondrial 5'(3')-deoxyribonucleotidase==
 
<StructureSection load='4l6a' size='340' side='right'caption='[[4l6a]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
Authors: Pachl, P., Brynda, J., Rezacova, P.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4l6a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L6A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4L6A FirstGlance]. <br>
Description: STRUCTURE OF HUMAN MITOCHONDRIAL 5'(3')-DEOXYRIBONUCLEOTIDASE
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4l6a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l6a OCA], [https://pdbe.org/4l6a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4l6a RCSB], [https://www.ebi.ac.uk/pdbsum/4l6a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4l6a ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NT5M_HUMAN NT5M_HUMAN] Dephosphorylates specifically the 5' and 2'(3')-phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from excess dTTP. Has only marginal activity towards dIMP and dGMP.
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Brynda J]]
[[Category: Pachl P]]
[[Category: Rezacova P]]
Retrieved from "https://proteopedia.org/4l6a"