4khm: Difference between revisions

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{{STRUCTURE_4khm|  PDB=4khm  |  SCENE=  }}
===HCV NS5B GT1A with GSK5852===
{{ABSTRACT_PUBMED_23672667}}


==About this Structure==
==HCV NS5B GT1A with GSK5852==
[[4khm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_subtype_1a Hepatitis c virus subtype 1a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KHM OCA].  
<StructureSection load='4khm' size='340' side='right'caption='[[4khm]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4khm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepatitis_C_virus_genotype_1a Hepatitis C virus genotype 1a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KHM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KHM FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PV:[4-({[5-CYCLOPROPYL-2-(4-FLUOROPHENYL)-3-(METHYLCARBAMOYL)-1-BENZOFURAN-6-YL](METHYLSULFONYL)AMINO}METHYL)-2-FLUOROPHENYL]BORONIC+ACID'>1PV</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4khm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4khm OCA], [https://pdbe.org/4khm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4khm RCSB], [https://www.ebi.ac.uk/pdbsum/4khm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4khm ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/B1PPP0_9HEPC B1PPP0_9HEPC]


==Reference==
==See Also==
<ref group="xtra">PMID:023672667</ref><references group="xtra"/><references/>
*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
[[Category: Hepatitis c virus subtype 1a]]
__TOC__
[[Category: RNA-directed RNA polymerase]]
</StructureSection>
[[Category: Kahler, K M.]]
[[Category: Hepatitis C virus genotype 1a]]
[[Category: Shotwell, J B.]]
[[Category: Large Structures]]
[[Category: Williams, S P.]]
[[Category: Kahler KM]]
[[Category: Boron]]
[[Category: Shotwell JB]]
[[Category: Hcv ns5b]]
[[Category: Williams SP]]
[[Category: Hcv polymerase]]
[[Category: P66]]
[[Category: P70]]
[[Category: Replication-replication inhibitor complex]]
[[Category: Rna dependent rna polymerase]]
[[Category: Rna directed rna polymerase]]
[[Category: Site iv inhibitor]]