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{{STRUCTURE_4jmr|  PDB=4jmr  |  SCENE=  }}
===A unique spumavirus gag N-terminal domain with functional properties of orthoretroviral Matrix and Capsid===
{{ABSTRACT_PUBMED_23675305}}


==About this Structure==
==A unique spumavirus gag N-terminal domain with functional properties of orthoretroviral Matrix and Capsid==
[[4jmr]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_foamy_virus Human foamy virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JMR OCA].  
<StructureSection load='4jmr' size='340' side='right'caption='[[4jmr]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4jmr]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_foamy_virus Human foamy virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JMR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JMR FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jmr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jmr OCA], [https://pdbe.org/4jmr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jmr RCSB], [https://www.ebi.ac.uk/pdbsum/4jmr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jmr ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GAG_FOAMV GAG_FOAMV] Involved in capsid formation and genome binding. Shortly after infection, interaction between incoming particle-associated Gag proteins and host dynein allows centrosomal targeting of the viral genome (associated to Gag), prior to nucleus translocation and integration into host genome.<ref>PMID:16160174</ref> <ref>PMID:12857789</ref>


==Reference==
==See Also==
<ref group="xtra">PMID:023675305</ref><references group="xtra"/><references/>
*[[Gag polyprotein 3D structures|Gag polyprotein 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Human foamy virus]]
[[Category: Human foamy virus]]
[[Category: Ball, N J.]]
[[Category: Large Structures]]
[[Category: Flower, T G.]]
[[Category: Ball NJ]]
[[Category: Goldstone, D C.]]
[[Category: Flower TG]]
[[Category: Taylor, I A.]]
[[Category: Goldstone DC]]
[[Category: Coiled-coil]]
[[Category: Taylor IA]]
[[Category: Env]]
[[Category: Gag]]
[[Category: Viral protein]]
[[Category: Viral protein-peptide complex]]
Retrieved from "https://proteopedia.org/4jmr"