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[[Image:2hqx.gif|left|200px]]<br /><applet load="2hqx" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2hqx, resolution 1.42&Aring;" />
'''Crystal structure of human P100 tudor domain conserved region'''<br />


==About this Structure==
==Crystal structure of human P100 tudor domain conserved region==
2HQX is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HQX OCA].  
<StructureSection load='2hqx' size='340' side='right'caption='[[2hqx]], [[Resolution|resolution]] 1.42&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2hqx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HQX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HQX FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.42&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hqx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hqx OCA], [https://pdbe.org/2hqx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hqx RCSB], [https://www.ebi.ac.uk/pdbsum/2hqx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hqx ProSAT], [https://www.topsan.org/Proteins/SECSG/2hqx TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SND1_HUMAN SND1_HUMAN] Functions as a bridging factor between STAT6 and the basal transcription factor. Plays a role in PIM1 regulation of MYB activity. Functions as a transcriptional coactivator for the Epstein-Barr virus nuclear antigen 2 (EBNA2).<ref>PMID:7651391</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hq/2hqx_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hqx ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Liu, Z J.]]
[[Category: Liu ZJ]]
[[Category: SECSG, Southeast Collaboratory for Structural Genomics.]]
[[Category: Silvennoinen O]]
[[Category: Silvennoinen, O.]]
[[Category: Wang BC]]
[[Category: Wang, B C.]]
[[Category: Xu H]]
[[Category: Xu, H.]]
[[Category: Yang J]]
[[Category: Yang, J.]]
[[Category: Zhao M]]
[[Category: Zhao, M.]]
[[Category: human p100 tudor domain]]
[[Category: protein structure initiative]]
[[Category: proteolytic fragment]]
[[Category: psi]]
[[Category: secsg]]
[[Category: southeast collaboratory for structural genomics]]
[[Category: structural genomics]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:44:44 2008''

Latest revision as of 10:00, 30 August 2023

Crystal structure of human P100 tudor domain conserved region

2hqx, resolution 1.42Å

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