3wcy: Difference between revisions
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==Murine Ifnar1 in complex with interferon-beta== | |||
<StructureSection load='3wcy' size='340' side='right'caption='[[3wcy]], [[Resolution|resolution]] 2.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3wcy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WCY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WCY FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wcy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wcy OCA], [https://pdbe.org/3wcy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wcy RCSB], [https://www.ebi.ac.uk/pdbsum/3wcy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wcy ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/INAR1_MOUSE INAR1_MOUSE] Associates with IFNAR2 to form the type I interferon receptor. Receptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves. | |||
==See Also== | |||
*[[Interferon 3D structures|Interferon 3D structures]] | |||
*[[Interferon receptor 3D structures|Interferon receptor 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | |||
[[Category: Hertzog PJ]] | |||
[[Category: Rossjohn J]] | |||
[[Category: Vivian JP]] | |||
[[Category: De Weerd NA]] | |||
Latest revision as of 13:05, 8 November 2023
Murine Ifnar1 in complex with interferon-beta
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