2hw2: Difference between revisions

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[[Image:2hw2.jpg|left|200px]]<br /><applet load="2hw2" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2hw2, resolution 1.45&Aring;" />
'''Crystal structure of Rifampin ADP-ribosyl transferase in complex with Rifampin'''<br />


==About this Structure==
==Crystal structure of Rifampin ADP-ribosyl transferase in complex with Rifampin==
2HW2 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_smegmatis Mycobacterium smegmatis] with <scene name='pdbligand=GLY:'>GLY</scene> and <scene name='pdbligand=RFP:'>RFP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/NAD(+)_ADP-ribosyltransferase NAD(+) ADP-ribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.30 2.4.2.30] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HW2 OCA].
<StructureSection load='2hw2' size='340' side='right'caption='[[2hw2]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
[[Category: Mycobacterium smegmatis]]
== Structural highlights ==
[[Category: NAD(+) ADP-ribosyltransferase]]
<table><tr><td colspan='2'>[[2hw2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycolicibacterium_smegmatis Mycolicibacterium smegmatis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HW2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HW2 FirstGlance]. <br>
[[Category: Single protein]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
[[Category: Baysarowich, J.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLY:GLYCINE'>GLY</scene>, <scene name='pdbligand=RFP:RIFAMPICIN'>RFP</scene></td></tr>
[[Category: Junop, M.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hw2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hw2 OCA], [https://pdbe.org/2hw2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hw2 RCSB], [https://www.ebi.ac.uk/pdbsum/2hw2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hw2 ProSAT]</span></td></tr>
[[Category: Wright, G.]]
</table>
[[Category: GLY]]
== Function ==
[[Category: RFP]]
[https://www.uniprot.org/uniprot/A0QRS5_MYCS2 A0QRS5_MYCS2]  
[[Category: adp-ribosylation]]
== Evolutionary Conservation ==
[[Category: protein-antibiotic complex]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: rifampin]]
Check<jmol>
[[Category: transferase]]
  <jmolCheckbox>
 
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hw/2hw2_consurf.spt"</scriptWhenChecked>
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:46:22 2008''
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hw2 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycolicibacterium smegmatis]]
[[Category: Baysarowich J]]
[[Category: Junop M]]
[[Category: Wright GD]]

Latest revision as of 09:34, 14 February 2024

Crystal structure of Rifampin ADP-ribosyl transferase in complex with Rifampin

2hw2, resolution 1.45Å

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