4la2: Difference between revisions
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==Crystal structure of dimethylsulphoniopropionate (DMSP) lyase DddQ== | |||
<StructureSection load='4la2' size='340' side='right'caption='[[4la2]], [[Resolution|resolution]] 1.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4la2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Ruegeria_lacuscaerulensis_ITI-1157 Ruegeria lacuscaerulensis ITI-1157]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LA2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LA2 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4la2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4la2 OCA], [https://pdbe.org/4la2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4la2 RCSB], [https://www.ebi.ac.uk/pdbsum/4la2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4la2 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/DDDQ_RUELI DDDQ_RUELI] Able to cleave dimethlysulfonioproprionate (DMSP) in vitro, releasing dimethyl sulfide (DMS). DMS is the principal form by which sulfur is transported from oceans to the atmosphere (PubMed:24395783, PubMed:24967457). The real activity of the protein is however subject to debate and it is unclear whether it constitutes a real dimethlysulfonioproprionate lyase in vivo: the very low activity with DMSP as substrate suggests that DMSP is not its native substrate (PubMed:24760823).<ref>PMID:24395783</ref> <ref>PMID:24760823</ref> <ref>PMID:24967457</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Ruegeria lacuscaerulensis ITI-1157]] | |||
[[Category: Li C]] | |||
[[Category: Zhang Y]] | |||
Latest revision as of 08:55, 20 March 2024
Crystal structure of dimethylsulphoniopropionate (DMSP) lyase DddQ
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