1e5g: Difference between revisions
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== | ==Solution structure of central CP module pair of a pox virus complement inhibitor== | ||
[[ | <StructureSection load='1e5g' size='340' side='right'caption='[[1e5g]]' scene=''> | ||
== Structural highlights == | |||
== | <table><tr><td colspan='2'>[[1e5g]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Vaccinia_virus_Copenhagen Vaccinia virus Copenhagen]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E5G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1E5G FirstGlance]. <br> | ||
[[1e5g]] is a 1 chain structure with sequence from [ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1e5g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e5g OCA], [https://pdbe.org/1e5g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1e5g RCSB], [https://www.ebi.ac.uk/pdbsum/1e5g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1e5g ProSAT]</span></td></tr> | |||
== | </table> | ||
< | == Function == | ||
[[Category: Vaccinia virus | [https://www.uniprot.org/uniprot/VCP_VACCC VCP_VACCC] Serves to protect the virus against complement attack by inhibiting both classical and alternative pathways of complement activation. Binds C3b and C4b. | ||
[[Category: Barlow | == Evolutionary Conservation == | ||
[[Category: Bromek | [[Image:Consurf_key_small.gif|200px|right]] | ||
[[Category: Henderson | Check<jmol> | ||
[[Category: Mullin | <jmolCheckbox> | ||
[[Category: Smith | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e5/1e5g_consurf.spt"</scriptWhenChecked> | ||
[[Category: Uhrin | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1e5g ConSurf]. | |||
<div style="clear:both"></div> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Vaccinia virus Copenhagen]] | |||
[[Category: Barlow PN]] | |||
[[Category: Bromek K]] | |||
[[Category: Henderson CE]] | |||
[[Category: Mullin NP]] | |||
[[Category: Smith BO]] | |||
[[Category: Uhrin D]] | |||
Latest revision as of 09:58, 20 March 2024
Solution structure of central CP module pair of a pox virus complement inhibitor
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