4k7q: Difference between revisions

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{{STRUCTURE_4k7q|  PDB=4k7q  |  SCENE=  }}
===Crystal Structure of AcrB Complexed with Linezolid at 3.5 Resolution===
{{ABSTRACT_PUBMED_23673416}}


==Function==
==Crystal Structure of AcrB Complexed with Linezolid at 3.5 Resolution==
[[http://www.uniprot.org/uniprot/ACRB_ECOLI ACRB_ECOLI]] AcrAB is a drug efflux protein with a broad substrate specificity.<ref>PMID:16915237</ref> <ref>PMID:16946072</ref> <ref>PMID:17194213</ref>
<StructureSection load='4k7q' size='340' side='right'caption='[[4k7q]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[4k7q]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K7Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K7Q FirstGlance]. <br>
[[4k7q]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K7Q OCA].  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZLD:N-{[(5S)-3-(3-FLUORO-4-MORPHOLIN-4-YLPHENYL)-2-OXO-1,3-OXAZOLIDIN-5-YL]METHYL}ACETAMIDE'>ZLD</scene></td></tr>
==Reference==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k7q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k7q OCA], [https://pdbe.org/4k7q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k7q RCSB], [https://www.ebi.ac.uk/pdbsum/4k7q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k7q ProSAT]</span></td></tr>
<ref group="xtra">PMID:023673416</ref><references group="xtra"/><references/>
</table>
[[Category: Escherichia coli k-12]]
== Function ==
[[Category: Gupta, G.]]
[https://www.uniprot.org/uniprot/ACRB_ECOLI ACRB_ECOLI] AcrAB is a drug efflux protein with a broad substrate specificity.<ref>PMID:16915237</ref> <ref>PMID:16946072</ref> <ref>PMID:17194213</ref>
[[Category: Hung, L W.]]
== References ==
[[Category: Kim, C Y.]]
<references/>
[[Category: Kim, H B.]]
__TOC__
[[Category: Murakami, S.]]
</StructureSection>
[[Category: Terwilliger, T C.]]
[[Category: Escherichia coli K-12]]
[[Category: Inner membrane resistance-nodulation-cell division efflux pump]]
[[Category: Large Structures]]
[[Category: Membrane protein-antibiotic complex]]
[[Category: Gupta G]]
[[Category: Hung LW]]
[[Category: Kim CY]]
[[Category: Kim HB]]
[[Category: Murakami S]]
[[Category: Terwilliger TC]]
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