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[[Image:2ikc.gif|left|200px]]<br /><applet load="2ikc" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2ikc, resolution 3.25&Aring;" />
'''Crystal structure of sheep lactoperoxidase at 3.25 A resolution reveals the binding sites for formate'''<br />


==About this Structure==
==Crystal structure of sheep lactoperoxidase at 3.25 A resolution reveals the binding sites for formate==
2IKC is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Ovis_aries Ovis aries] with <scene name='pdbligand=NAG:'>NAG</scene>, <scene name='pdbligand=CA:'>CA</scene>, <scene name='pdbligand=CO3:'>CO3</scene>, <scene name='pdbligand=HEM:'>HEM</scene> and <scene name='pdbligand=FMT:'>FMT</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Peroxidase Peroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.7 1.11.1.7] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IKC OCA].  
<StructureSection load='2ikc' size='340' side='right'caption='[[2ikc]], [[Resolution|resolution]] 3.25&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2ikc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Ovis_aries Ovis aries]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IKC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IKC FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.25&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CO3:CARBONATE+ION'>CO3</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ikc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ikc OCA], [https://pdbe.org/2ikc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ikc RCSB], [https://www.ebi.ac.uk/pdbsum/2ikc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ikc ProSAT]</span></td></tr>
</table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ik/2ikc_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ikc ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Lactoperoxidase|Lactoperoxidase]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Ovis aries]]
[[Category: Ovis aries]]
[[Category: Peroxidase]]
[[Category: Sharma S]]
[[Category: Single protein]]
[[Category: Sheikh IA]]
[[Category: Sharma, S.]]
[[Category: Singh AK]]
[[Category: Sheikh, I A.]]
[[Category: Singh N]]
[[Category: Singh, A K.]]
[[Category: Singh TP]]
[[Category: Singh, N.]]
[[Category: Singh, T P.]]
[[Category: CA]]
[[Category: CO3]]
[[Category: FMT]]
[[Category: HEM]]
[[Category: NAG]]
[[Category: formate]]
[[Category: heme]]
[[Category: peroxidase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:53:31 2008''

Latest revision as of 08:13, 30 October 2024

Crystal structure of sheep lactoperoxidase at 3.25 A resolution reveals the binding sites for formate

2ikc, resolution 3.25Å

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