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{{STRUCTURE_4lb0|  PDB=4lb0  |  SCENE=  }}
===Crystal structure of a hydroxyproline epimerase from agrobacterium vitis, target efi-506420, with bound trans-4-oh-l-proline===


==About this Structure==
==Crystal structure of a hydroxyproline epimerase from agrobacterium vitis, target efi-506420, with bound trans-4-oh-l-proline==
[[4lb0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Agrobacterium_vitis_s4 Agrobacterium vitis s4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LB0 OCA].  
<StructureSection load='4lb0' size='340' side='right'caption='[[4lb0]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
[[Category: Agrobacterium vitis s4]]
== Structural highlights ==
[[Category: Almo, S C.]]
<table><tr><td colspan='2'>[[4lb0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Agrobacterium_vitis_S4 Agrobacterium vitis S4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LB0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LB0 FirstGlance]. <br>
[[Category: Bhosle, R.]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
[[Category: Chowdhury, S.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=HYP:4-HYDROXYPROLINE'>HYP</scene></td></tr>
[[Category: EFI, Enzyme Function Initiative.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lb0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lb0 OCA], [https://pdbe.org/4lb0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lb0 RCSB], [https://www.ebi.ac.uk/pdbsum/4lb0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lb0 ProSAT]</span></td></tr>
[[Category: Evans, B.]]
</table>
[[Category: Gerlt, J A.]]
== Function ==
[[Category: Glenn, A S.]]
[https://www.uniprot.org/uniprot/4HYPE_AGRVS 4HYPE_AGRVS] Catalyzes the epimerization of trans-4-hydroxy-L-proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp). May be involved in a degradation pathway of t4LHyp. Can also catalyze the epimerization of trans-3-hydroxy-L-proline (t3LHyp) to cis-3-hydroxy-D-proline (c3DHyp) in vitro. Displays no proline racemase activity.<ref>PMID:24980702</ref>
[[Category: Hammonds, J.]]
== References ==
[[Category: Hillerich, B.]]
<references/>
[[Category: Imker, H J.]]
__TOC__
[[Category: Love, J.]]
</StructureSection>
[[Category: Morisco, L L.]]
[[Category: Agrobacterium vitis S4]]
[[Category: Obaidi, N F.Al.]]
[[Category: Large Structures]]
[[Category: Seidel, R D.]]
[[Category: Al Obaidi NF]]
[[Category: Sojitra, S.]]
[[Category: Almo SC]]
[[Category: Stead, M.]]
[[Category: Bhosle R]]
[[Category: Toro, R.]]
[[Category: Chowdhury S]]
[[Category: Vetting, M W.]]
[[Category: Evans B]]
[[Category: Washington, E.]]
[[Category: Gerlt JA]]
[[Category: Wasserman, S R.]]
[[Category: Glenn AS]]
[[Category: Efi]]
[[Category: Hammonds J]]
[[Category: Enzyme function initiative]]
[[Category: Hillerich B]]
[[Category: Isomerase]]
[[Category: Imker HJ]]
[[Category: Proline racemase family]]
[[Category: Love J]]
[[Category: Proposed 3-oh and 4-oh proline epimerase]]
[[Category: Morisco LL]]
[[Category: Structural genomic]]
[[Category: Seidel RD]]
[[Category: Sojitra S]]
[[Category: Stead M]]
[[Category: Toro R]]
[[Category: Vetting MW]]
[[Category: Washington E]]
[[Category: Wasserman SR]]
Retrieved from "https://proteopedia.org/4lb0"